Dr Kaushik Deb Honored with 3D PRINTING Award

An Award ceremony was organized recognizing excellence in 3D printing held with the 3D PRINTING WORLDTHINK –BOARD- MEDICAL AND HEALTHCARE ON 4 MARCH 2017 at The Lalit Mumbai, which was organized by Dr. Shibu John, CEO.  & Founder of Trinity Media & Marketing Solutions.

Dr.Kaushik Deb, Founder Director and CEO,  Diponed BioIntelligence was  honored with “3D PRINTING AWARD 2017-MEDICAL SERVICES & SOLUTIONS COMPANY OF THE YEAR” for the company’s contribution in medical services in 3D printing orthotics, prosthetics development of bio-inks, 3D printed medical implants, 3D devices for the stem cell activation and processing.

A healthcare revolution is taking place throughout the world, founded on the ability to create highly personalized 3D printed medical devices and patient-specific surgical simulation and direct printing of individualized implants and customized instrumentation. Diponed BioIntelligence was awarded “Uchattar Avishkar Yogana” funding recently by the Government of India Ministry of Health in corporation with IFT Hyderabad for indigenously developing 3D printed orthotics. Diponed is a personalized Healthcare Company and is also using 3D printing for personalized prosthetics development. Dr. Kaushik Deb said “Such advances in personalized 3D printed prosthetics can help patients in having a better quality of life.”

3D Printing is an additive manufacturing process that creates a physical object from a digital design. There are different 3D printing technologies, but all are based on the same principle: a digital model is turned into a solid three-dimensional physical object by adding material layer by layer. 3D printing starts with a digital file derived from computer aided design (CAD) software. Once a design is completed, it must then be exported as a standard tessellation language (STL) file, meaning the file is translated into triangulated surfaces and vertices. The STL file then has to be sliced into hundreds – sometimes thousands – of 2-D layers. A 3D printer then reads the 2-D layers as building blocks which it layers one atop the other, thus forming a three dimensional object.

A 3D printer can also dispense biological materials making bio-printing possible. Bio-printing can be achieved with layer-by-layer positioning of biomaterials as well as living cells. The precise spatial control of the functional materials allows for the fabrication of 3D tissue structures such as skin, cartilage, tendon, cardiac muscle, and bone. The process starts with the selection of the corresponding cells for the tissue. Next, a viable bio-ink material is prepared from a suitable cell carrier and media. Finally, the cells are printed for subsequent culture into the required dimensions. In contrast to conventional 3D printing, 3D bio-printing is more complex in terms of the selection of materials, cell types, growth/differentiation factors, and sensitivity of the living cells construction.

In 2014 alone, the 3D-printing industry grew by 35.2%. And although the industry saw a slight slowdown in 2015, innovations with 3D-printed products are visible among a wide range of industries. But perhaps the most exciting advances in 3D printing can be found in the world of medicine, where 3D printing is starting to shake things up, especially as the cost of 3D printing drops and the technology becomes more accessible.

There are plenty of other advances in the field of 3D bio-printing, and many of them have been a part of successful surgeries and treatments. In cancer treatment alone, 3D printing is making huge leaps forward. In 2014, researchers developed a fast, inexpensive way to make facial prostheses for patients who had undergone surgery for eye cancer, using facial scanning software and 3D printing. Just this past year, in 2015, another team of researchers found that it is possible to print patient-specific, biodegradable implants to more effectively cure bone infections and bone cancer.

Bio-printing has the potential of generating tissue constructs for regenerative therapy and transplantation, furthermore, printing cellularized hydro-gels can be used to create construct that bio-mimic natural soft tissues. “In Diponed we are working with many foreign laboratories and universities to 3D print functional stem cells and tissues like sking chondrocytes, osteoblasts and hepatocytes” said Dr. Kaushik Deb.

In the processes of bio-printing, bio-ink developments are one of the most challenging issues. For 3D bio-printing, the set bio-ink is required to hold the vertical print and bear the weight of the emerging structure. Bio-ink is required to interact with cells both in vitro and in vivo.

Cell printing bio-inks have the further requirements; to maintain cell integrity and viability during resuspension and passage through the print head and provision of a suitable environment for cell growth and function within the printed scaffold. Both natural and synthetic polymers are chosen. Natural extracellular matrix (ECM) components have been used widely such as collagen, fibrin, gelatin, hyaluronic acid, etc. Synthetic biocompatible polymers such as pluronic F127, polyethylene oxide and polyethylene glycol are used.

The great potential for the bio-printing differentiation of stem cells will hopefully be realized for use in regenerative therapy, with an ultimate goal of fabricating customized tissue constructs and complete organs seeded with host stem cells for implantation. Some interesting in vivo studies have shown promising results for 3D printing for skin regeneration.

It is hoped that that bio-printing stem cells will eventually produce patient specific, bespoke constructs for regenerative therapy. This may include matching the construct to a specific lesion size and shape, and even producing complete organs for implantation. It is recognized that this technology is still in its early days. One particular challenge that needs to be overcome is the slow fabrication rate. It has been estimated with current bio-printing equipment, the fabrication of a full human liver (a construct of 1000 cm3) would take up to 3 days to complete. This lengthy production time may reduce the stem cell viability. As current bio-printing techniques struggle to print concentrations up to 107 cells/ml, hence improved technology will be required to meet the density of 5 to 10 × 108 cells/ml they consider sufficient for tissue and organ function. The use of stem cells in tissue bio-printing has the important advantage when fabricating organs populated by non-proliferative cells, such as cardiac tissue, as stem cells can be expanded in vitro in order to accumulate sufficient numbers prior to differentiation. This has the potential of becoming more efficient as IPSC (Induced pluripotent stem cells) technology advances. Diponed Biointelligence is a predictive, preventive, participating and personalized medicine (PGM) company. The company is focused on developing innovative services and products to serve unmet medical needs. (Visit us at: www.diponed.com)

Aim for a healthy weight

Dr. Kaushik Deb

The chances of risking your health with several diseases and poor health conditions are higher if someone is overweight or obese. It increases the risk for attracting many diseases. The more weight you gain, the chances are higher to suffer from heart related diseases, high blood pressure, diabetes, liver related diseases, poor digestions etc. On the other side a healthy and balanced weight has several benefits- it enables you to feel good about yourself, it gives you more energy and focus and most importantly it helps you to lower your risk for suffering from the other problems.

You need to change the way you approach for weight loss, it can help you in being more successful at losing it. Most people willing to lose weight focus on one thing, i.e. weight loss. However, if you set your goals, start to eat healthy foods and avoid junk foods, become more physically active and disciplined, and get to know how to change behaviors and patterns, then you may be more successful at losing weight. Over time, these changes will become routine and part of your everyday life. The first step to losing and maintaining the weight is to set the right goal.

You must keep the right balance between the calories or energy that you get from food items and beverages with the calories that you use to keep your body going and physically active.

You must follow a healthy eating plan so it gives your body the nutrients it needs every day and helps you to stay within your daily calorie level. The balanced eating plan will also lower your risk for heart disease and such other conditions as high blood pressure and high blood cholesterol levels. A healthy eating plan includes- fruits, vegetables, whole grains, and fat-free or low-fat milk and milk products. It also includes lean meats, poultry, fish, beans, eggs, and nuts. Cutting back on calories is a very important part of a healthy eating plan to lose weight. You must select the foods that are lower in fats, especially saturated and trans fats, cholesterol, and added sugars. To lose 1–2 pounds in a week, daily intake should be reduced by 500 to 1,000 calories. Staying physically active and eating less calories will help you lose weight in a right way and keep the weight off over time.

In today’s competitive world the people have developed a habit of ignoring these facts. They lack adequate focus on their health and fitness, but in long run it is bound to severally affect their health conditions. Dr. Kaushik Deb of DiponEd BioIntelligence, a leading  predictive-, preventive-, participatory-, and personalized- medicine (P4M) company suggest their highly successful product MT- SlimEd. According to Dr.Kaushik D. Deb- MT- SlimEd is 100% botanical and it helps in increasing metabolism and reduces 5KGs in just 3 months. Also DiponEd BioIntelligence R&D team is constantly working in this direction to assist the people for wellbeing and healthiness in their life.

BLESS DOCTORS MEDICAL CENTER (BDMC) Brings New Therapies for Chronic Joint Pain Treatments in Rural India

Bless Doctors Medical center/ clinics (BDMC) is a unit of DiponEd BioIntelligence, a health care company that focuses on developing cost effective solutions for unmet and difficult to treat medical conditions. Joint pain, sport injuries can all be treated with a new therapeutic approach. Other diseases like Osteoarthritis, Rheumatoid arthritis etc are also treated and managed well with propitiatory low cost immunotherapies developed by doctors at DiponEd BioIntelligence Bangalore. The first unit of BDMC has been started in Chakdaha Nadia and will be spread to neighboring towns soon (Krisnanagar, Kalyani, Palpara, Ranaghat, Bongaon, Kanchrapara etc).

People suffering with pain in the joints, knees and with other fitness problems due to such unavoidable factors like age, environmental pollution, and stress in job, business or occupational hazards are common in every household. BDMC’s aim is to bring in the latest medical treatments to the people suffering from such problems in semi urban and rural areas of WB. BDMC enables its patients to send their reports for opinions from doctors in Bangalore, Hyderabad, Chennai or Mumbai. BDMC unit has a team of one qualified doctor a Nurse and a Manger to offer primary care and opinion. The team helps patients with diagnosis, treatments, tests and 2nd opinion from doctors in South India.

Dr. Kaushik D. Deb the founder and CEO of DiponEd and BDMC said “We offer to treat patients in various villages in and around Chakdaha. Patients will be able to enjoy cutting edge but low cost treatments that people enjoy in Bangalore, Hyderabad, Mumbai and Chennai. We have the best team of orthopedic doctors of international fame on board to help us like Dr Appa Rao wellknown for Rhematoid arthritis treatments, Dr Srikant wellknown for Joint Replacement surgeries, treatment of arthritis and AVN , Dr S. Chari for general injuries and wounds and Dr NK Biswas for spinal cord / lower back slip discs treatments."

Doctors on board at DiponEd BioIntelligence, are well known internationally for their treatments in Osteoarthritis, Sports injuries and Rhematoid arthritis etc. Here are the following treatments and procedures (examples) done at the BDM centers or clinics for chronic pain management:

1.     Osteoarthritis

The high costing replacement surgeries per knee of patients at Grade 1, 2 or 3 with Arthritis of the knees can be avoided and prevented if treated earlier by our process. Biological therapies for focal knee osteoarthritis, such as platelet-rich plasma, have been proposed to improve clinical and structural outcomes by delivering a high concentration of growth factors that mediate healing and remodeling.

2.     Joint replacement surgeries

Patients who have severe pain in hip and the knees and have been detected with Grade 4 Osteoarthritis (OA) of knees or Avascular Necrosis of the femoral heads (AVN) for hip joints can take advantage of total hip and knee replacements at our Bangalore based unit. Internationally renowned orthopedic joint replacement surgeon Dr Srikant runs joint replacement not for high profit but for high quality.

3.     Spinal Slip and Protruded Disc treatments

BDMC provides treatments which are alternatives to very expensive surgeries for patients suffering from lower back pain problems. Treatments at BDMC are based on European and US based non invasive procedures that use pain relief patches based on modern medicine and nanotechnology.

4.     Soft tissue and Sports injuries

Heavy weight lifting, agricultural farming, cricket, wrestling, fast running, playing football etc. sports, can cause problems like muscle sprains and ligament tears etc. These injuries can be very painful and take longer time to recover. Doctors at BDMC look at individual cases carefully and offer suitable solutions.

5.     Rheumatoid arthritis (RA)

RA is a debilitating disease and almost makes the patient immobile with pain and other bone deformities. BDMC offers more advanced treatments including a new immunotherapy for such autoimmune diseases like RA. Each injection required is only for a couple of hundred rupees, and the full treatment can be done for few thousand Rs per month.

DR. KAUSHIK DEB EULOGIZED HIM AND SAID “THIS IS A PROUD MOMENT FOR ALL OF US IN DIPONED

Dr. Anan Shetty, a renowned Indian-origin orthopaedic surgeon has been awarded with the prestigious Hunterian Professorship and the Medal for 2017 for his research on stem cells in articular cartilage repair by UK's Royal College of Surgeons. Dr Anan Shetty is a knee surgeon in the UK and a Chair and Director of stem cell research at Canterbury Christ Church University.

As one of the most prestigious international awards for surgeons of eminence who have richly contributed to the field of surgery by original research or innovations, recognising significant contributions made to surgical, anaesthetic or dental science, it has been awarded to Professor Shetty for his research on stem cells in articular cartilage repair. On being awarded with the highly – regarded annual award in the field of surgery, Professor Shetty, Consultant Orthopaedic Surgeon, comments, “I’m honoured to accept the Hunterian Professorship and Medal for 2017 from the Royal College of Surgeons. Using stem cells to support the growth of new cartilage in joints has the potential to broaden the possibilities of treatment for patients who require knee replacements. The research we have undertaken demonstrates that the re-growth of cartilage in damaged knees can delay the need for knee replacement surgery and in some cases prevent it. This could have a significant impact on patients, especially younger people, if they do not have to undergo surgery.”

Dr. Shetty is the founder and director of DiponED. DiponEd BioIntelligence is a predictive-, preventive-, participatory-, and personalized- medicine (P4M) company. He has contributed in the P4M approach of DiponED BioIntelligence which is clearly set to improve the current health care and wellness systems and concepts in the coming years. DiponED Chief Executive, Dr. Kaushik Deb eulogized him and said “this is a proud moment for all of us in DiponEd as well as for the Orthopedics fraternity in India. Dr Anan Shetty has trained a lot of young doctors in India in doing stem cells implants, autologus chondrocyte implants etc. He is a champion in treating osteo chondral defects.”

Apart from training orthopaedic surgeons at the Royal College of Surgeons of England, Dr Shetty is leading world class research in knee surgery. Dr. Anan Shetty has undertaken some of the most complex revision knee surgery and limb reconstruction surgeries. His reputation as a knee surgeon and orthopaedic teacher attracts surgeons and patients from all over the world. 

Source:http://drkaushukdebdiponedbiointelligence.weebly.com/blog/dr-kaushik-deb-eulogized-him-and-said-this-is-a-proud-moment-for-all-of-us-in-diponed